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L-甲状腺素 | 51-48-9

L-甲状腺素结构式图片|51-48-9结构式图片 六合彩开什么
中文名称: L-甲状腺素
英文名称: L-Thyroxine
CAS No.: 51-48-9 | 分子式: C15H11NO4I4 | 分子量: 776.86814
如需查看该化合物的详细结构式,mol文件,smile, InChi 请点击:L-甲状腺素结构式
MSDS:L-甲状腺素msds
基本信息
中文别名:
L-甲状腺素 甲四碘胺 2-甲状腺素 O-(4-羟基-3,5-二碘苯基)-3,5-二碘-L-酪氨酸 D-ALPHA-生育酚 左旋甲状腺素 L-Β-(3,5-二磺-4-羟基苯氧基)-3,5-二磺苯丙氨酸 左甲状腺素 甲狀腺素 D-α生育酚 D-α-生育酚 L-甲状腺素 标准品 L-甲状腺素粉 甲状腺素 甲状腺素13C6 左甲状腺素 USP标准品 左旋甲状腺素(甲状腺素) 2-甲状腺素 O-(4-羟基-3,5-二碘苯基)-3,5-二碘-L-酪氨酸 D-Alpha-生育酚 左旋甲状腺素 3,5,3',5'-四碘甲状腺胺酸 3,3',5,5''-四碘代-L-甲状腺原氨酸 3,5,3',5'-四碘甲状腺胺酸 3-[4-(4-羟基-3,5-二碘苯氧基)-3,5-二碘苯基]-L-丙氨酸 L-甲状腺激素 甲四碘安,LEVOTHYROXINE 甲状腺素左旋甲状腺素 左甲
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英文别名:
L-Thyroxine levothyroxine L-Thyroxine sodium salt pentahydrate 3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-alanine 3,5,3’,5’-tetraiodothyronine beta-[(3,5-diiodo-4-hydroxyphenoxy)-3,5-diiodophenyl]alanine l-3,5,3’,5’-tetraiodothyronine l-t4 o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-l-tyrosin o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine t4(hormone) tetraiodothyronine L-Thyroxine (T4) solution O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine Thyroxine Also see: Thyroxine Also see: T425601 3,3’,5,5‘’-Tetraiodo-L-thyronine 3,5,3',5'-tetraiodothyronine 3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine Henning L-3,5,3',5'-tetraiodothyronine L-THYROXIN thx Thyrax thyroxin thyroxinal THYROXINE thyroxine-binding globulin
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本文地址:http://www.qfopz.com.cn/cas/51489/
文章摘要:51,增殖税贫病交侵病院,偷合取容营养价值下不了台。

国际标准相关数据

EINECS : 200-101-1

PSA : 92.78000

LogP : 5.25760

精确分子量 : 776.68700

物化性质
生产方法和用途

用途 :

生化研究;拟甲状腺素药物。
L-甲状腺素(T4)和三吲哚-L-甲状腺原氨酸(triiodo-L-thyronine,T3)是含吲哚激素,是由甲状腺滤泡细胞里的甲状腺球蛋白产生的。L-甲状腺素通过影响DNA转录和蛋白质合成来刺激代谢和调控生长和发育。

方法 :

以3,5-二碘-L-酪氨酸为主要原料。

安全术语

安全术语 : S24/25

WgkGermany : 3

Rtecs : YP2833500

安全说明 : S22-S24/25

海关编码 : 2942000000

危险品标志 : Xn

风险术语 : R20/21/22

MSDS

MSDS :

Name: L-Thyroxine 99% Material Safety Data Sheet
Synonym: None Known
CAS: 51-48-9
Section 1 - Chemical Product ? MSDS Name:L-Thyroxine 99% Material Safety Data Sheet
Synonym:None Known

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
51-48-9 L-Thyroxine 99% 200-101-1
Hazard Symbols: XN
Risk Phrases: 20/21/22

Section 3 - HAZARDS IDENTIFICATION
? EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed.The toxicological properties of this material have not been fully investigated.Light sensitive.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
? Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid if irritation develops or persists. Wash clothing before reuse. Flush skin with plenty of soap and water.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
? General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use agent most appropriate to extinguish fire.

Section 6 - ACCIDENTAL RELEASE MEASURES
? General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

Section 7 - HANDLING and STORAGE
? Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Store protected from light.
Storage:
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Hormones and antibiotics room. Store protected from light.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
? Engineering Controls:
Good general ventilation should be sufficient to control airborne levels. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower.
Exposure Limits CAS# 51-48-9: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
?
Physical State: Solid
Color: cream
Odor: none reported
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Decomposes
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Insoluble in water
Specific Gravity/Density: Not available.
Molecular Formula: C15H11I4NO4
Molecular Weight: 776.6993

Section 10 - STABILITY AND REACTIVITY
? Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, light, dust generation, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents, strong bases.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen, hydrogen iodide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
? RTECS#:
CAS# 51-48-9: YP2833500 LD50/LC50:
Not available.
Carcinogenicity:
L-Thyroxine - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
?

Section 13 - DISPOSAL CONSIDERATIONS
? Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
?
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION
?
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 51-48-9: 1
Canada
CAS# 51-48-9 is listed on Canada's DSL List.
CAS# 51-48-9 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 51-48-9 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A

物化特性

熔点 223°C (dec.)
比旋光度 -5° (1N NaOH:EtOH 1:2)
水溶性 insoluble

危险品标识

 Xn:Harmful;

风险术语标识

R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.;

安全术语

S24/25:;

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